KMID : 0363320100310030467
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Journal of Korean Oriental Internal Medicine 2010 Volume.31 No. 3 p.467 ~ p.476
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A Study on the Correlation of Atherosclerosis Risk Factor and Pulse Wave Velocity(PWV) of Carotid-Femoral Artery With Sasang Constitution
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Im Eun-Young
Lee Je-Won Chang Woo-Seok Baek Kyung-Min Cheon Woo-Hyun Chung In-Kwon
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Abstract
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Object : The purpose of this study was to investigate the correlation of atherosclerosis risk factors and pulse wave velocity (PWV) of carotid-femoral artery with Sasang constitution. This study also aimed to investigate the relationship between PWV and risk factors of atherosclerosis, including serum cholesterol and homosisteine, hs-CRP.
Methods:We enrolled 160 patients without experience strokes who visited our hospital for a medical examination from January 1, 2008 to April 30, 2010 except patients whose body constitutions were undetermined according to QSCCII. We investigated the correlation between serum cholesterol values, blood pressure, body mass index(BMI), homosistein, hs-CRP and PWV. Pearson¡¯s correlation and partial correlation analysis were applied to examine the relationship between PWV and risk factors of atherosclerosis.
Result:Among the 160 subjects, 54 were Taeumin, 54 were Soyangin, and 52 were Soeumin. The prevalences of high BMI (P-value <0.01), high hs-CRP(P-value <0.05), and high PWV(P-value <0.05) of Taeumin were higher than those of the other constitutions. PWV of carotid-femoral artery was significantly different among the three constitutional groups(Taeumin: , Soyangin: , Soeumin: )(P-value <0.05). This research has show a statistical significance between the average amount of carotid-femoral artery PWV that is higher in Taeumin. Age factor of Taeumin was the effective determinant of the increase of mean PWV of carotid-femoral arteries.
Conclusions:There were significant differences in the prevalence of atherosclerosis according to Sasang constitution. This study showed that atherosclerosis was more prevalent in Taeumin. Therefore, according to our results, risk of atherosclerosis was higher in Taeumin than among other constitutions.
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KEYWORD
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Pulse wave velocity(PWV), Sasang Constitutional Medicine(SCM), atherosclerosis, risk factor
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